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Apigenin
Apigenin is a bioflavonoid compound (specifically a flavone) which is found in a wide variety of plants and herbs. It is highly abundant in chamomile, and may possess anxiety-reducing effects when consumed. At even higher doses, it may have sedative effects.
 
The calming effect of Apigenin is partially due to its ability to bind the GABAA receptor and act as a partial modulator. It likely potentiates (and is potentiated by) other flavonoids due to its complex CYP enzyme interactions in the liver. Apigenin also is known for its mood-boosting effects and some studies indicate it may normalize the ERK/CREB/BDNF pathway and enhance BDNF expression in certain cases. This may account for some of its cognition-enhancing effects.

Apigenin

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  • What is Apigenin?

    Apigenin is a common flavonoid found in a range of plants, including chamomile (Matricaria recutita). The traditional use of chamomile tea for calming and relaxation has led to  investigations of its active constituents, including apigenin. Apigenin is the most prevalent flavonoid in Chamomile (both Roman and German varieties) and believed to be responsible for a majority of its relaxing effects. Chamomile is a staple of a variety of traditional medicines across the globe.

    Apigenin Benefits and Uses

    Studies have shown that Apigenin may have the following benefits:

    • Promotes a positive mood and feelings of calm
    • Supports healthy sleep patterns
    • Acts as an anti-inflammatory

    Additional Information on Apigenin

    Apigenin was found to have anxiolytic properties, and it competitively inhibited the binding of flunitrazepam to brain membranes without influencing the binding of muscimol to GABAA receptors. The calming effect of Apigenin is partially due to its ability to bind the GABAA receptor and act as a partial modulator. It likely potentiates (and is potentiated by) other flavonoids due to its complex CYP enzyme interactions.

    Where to buy Apigenin?

    Austinootropics offers high-quality Apigenin powder. Our Apigenin has been lab-tested and verified for both product purity and identity.

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